منابع مشابه
Itraconazole versus amphotericin B plus nystatin in the prophylaxis of fungal infections in neutropenic cancer patients.
The efficacy and safety of itraconazole oral solution and a combination of amphotericin B capsules plus nystatin oral suspension were compared in the prophylaxis of fungal infections in neutropenic patients. In an open, randomized, multicentre trial, 144 patients received itraconazole oral solution 100 mg bd, and 133 patients received amphotericin B 500 mg tds plus nystatin 2 MU qds. Overall, 6...
متن کاملOral Nystatin: An Effective Prophylaxis for Fungal Infection in Preterm Babies in a Tertiary Level Hospital
Candida is a common cause of oral mucous membrane and skin infections in newborn infants. Disseminated candidiasis and Candidemia have become a frequent problem in neonatal intensive care unit [1]. Candida species are frequently encountered as part of the human commensal flora. Colonization by Candida spp. is the most impor tant risk factor for development of Candidemia and IFI in pre mature in...
متن کاملOral nystatin prophylaxis in surgical/trauma ICU patients: a randomised clinical trial
INTRODUCTION Candida prophylaxis in ICU is still a matter of debate. Oral chemoprophylaxis has been advocated to reduce the incidence of Candida colonisation and infection. METHODS We performed a randomised trial studying a single drug (nystatin) versus control in surgical/trauma ICU patients. Multiple-site testing for fungi was performed in each patient on ICU admission (T0) and subsequently...
متن کاملTopical nystatin prophylaxis: a likely viable measure for reducing impact of candidemia in neurosurgical patients with early tracheostomy intubation
topical antifungal prophylaxis [1-4]. For this reason we read with interest the paper published by Giglio and colleagues [5] underlining the ability of oral nystatin to reduce fungal colonization in surgical/trauma ICU patients. In our experience, we observed a dramatic increase of candidemia prevalence in neurosurgical ICU patients after implementation of early tracheostomy (from 2.2% to 9.7%)...
متن کاملDominant mutation for nystatin resistance in yeast.
In general, attempts to isolate strains of Candida albicans resistant to the commonly employed antifungicide nystatin have been unsuccessful (M. L. Littman, M. A. Pisano, and R. M. Lancaser, Antibiotics Ann. 1957-58, p. 981, 1958; C. K. J. Paniker, P. V. Kurup, and K. Indira Devi, Indian J. Med. Res. 51:846, 1963). A few strains, however, have yielded variants exhibiting threeto fourfold resist...
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ژورنال
عنوان ژورنال: Clinical Microbiology Reviews
سال: 1997
ISSN: 0893-8512,1098-6618
DOI: 10.1128/cmr.10.2.368